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May 04.2025

2 Minutes Read

Debate Ignites Over NIH’s Use of Old Technology for Universal Flu Vaccine

Glass vials on production line for universal flu vaccine development.

Outdated Technology in Modern Vaccine Development?

As the National Institutes of Health (NIH) gears up to invest half a billion dollars into developing a universal flu vaccine, many experts in the field are feeling uncertain. The approach being used relies on whole killed viruses, a technique that dates back to the mid-20th century. This trend alarmingly prompts scientists to question if we are moving forward or taking a step back.

As highlighted by a scientist involved in vaccine development, this method is reminiscent of the first polio vaccine created by Jonas Salk, a technique many argue has been surpassed by modern, more efficient production methods. "There is incredible work going on. This is not it," said another anonymous researcher, encapsulating the shared concern among their peers.

Concerns Around Funding and Approval

Compounding the issue is the way this funding was awarded. Since the project is led by NIH scientists themselves, it bypassed the rigorous peer-review process typically required for similar research projects. This has led to accusations of favoritism, with one critic labeling the situation as "incestuous." Veterans in the field, like Stanley Plotkin, are left wondering about the project's vetting and whether it truly merits such a substantial financial commitment.

The stakes are high, especially given that this vaccine aims to protect against a range of potentially dangerous flu strains. Yet, initial findings from Phase 1 trials have shown only modest effectiveness against four flu subtypes. Given the urgency of improving flu vaccines, many scientists believe a more innovative approach is crucial.

The Path Forward: Innovation is Key

Investing in outdated techniques raises pertinent questions about what this means for the future of vaccine development. The scientific community collectively recognizes the need for more dynamic and adaptable methods, which are essential for combating rapidly evolving pathogens. If health agencies like the NIH aim to prepare for future pandemics, pivoting towards cutting-edge technology rather than retrogressive approaches could be critical.

The NIH project highlights a crucial moment in vaccine development, reminding us that innovation is the key to triumphing over health crises in the years to come.

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Debate Ignites Over NIH’s Use of Old Technology for Universal Flu Vaccine

Outdated Technology in Modern Vaccine Development?

Concerns Around Funding and Approval

The Path Forward: Innovation is Key

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